Reducing Contamination Risks With PCR Laminar Flow Cabinets

PCR (Polymerase Chain Reaction) amplification allows researchers to perform critical DNA/RNA segment detection to diagnose diseases or uncover genetic disorders.

 

Its ability to target specific segments in genetic material means that PCR testing can be used on even minute samples as the amplification process makes many identical copies of the DNA or RNA fragments.

 

Though highly accurate, PCR is extremely sensitive to contamination. In the case of virus detection for diagnosis, this can lead to false results. In light of the current COVID-19 pandemic, erroneous results can lead to significant problems. While these contaminated samples in these cases can often be replaced fairly easily, that is not always the case. Genotyping is commonly used as part of in vitro fertilization (IVF) to test embryos for abnormalities before transfer. Only a few cells can be taken from each embryo, and once biopsied, embryos are cryogenically frozen. In short, the sample used is irreplaceable.

 

When thermocyclers, or PCR machines, are used within a PCR Laminar Flow Cabinet, cross-contamination can be greatly reduced for sensitive applications.

 

Air Science PCR Laminar Flow Cabinets